| 2021 | Committee Against Anti-Asian Violence, Inc. | $50,000 | Special Projects |
| 2021 | Stefanie Stantcheva | $200,000 | Andrew Carnegie Fellows |
| 2021 | Gabriel Zucman | $200,000 | Andrew Carnegie Fellows |
| 2021 | Francoise Hamlin | $199,200 | Andrew Carnegie Fellows |
| 2021 | EducationCounsel | $200,000 | Education |
| 2021 | Beth Bailey | $200,000 | Andrew Carnegie Fellows |
| 2021 | From the Heart Productions, Inc. | $100,000 | Special Projects |
| 2021 | Community Partners | $40,000 | Education |
| 2021 | American Association of Collegiate Registrars and Admissions Officers | $20,000 | Education |
| 2021 | James W. Foley Legacy Foundation, Inc. | $25,000 | Special Projects |
| 2021 | Reach Out and Read Inc. | $25,000 | Special Projects |
| 2021 | Build UP | $50,000 | Education |
| 2021 | Teachers College, Columbia University | $125,000 | Special Projects |
| 2021 | Kevin Thomas | $200,000 | Andrew Carnegie Fellows |
| 2021 | Association of African Universities | $75,000 | International Peace and Security |
| 2021 | Gillen Wood | $200,000 | Andrew Carnegie Fellows |
| 2021 | Kristina Douglass | $200,000 | Andrew Carnegie Fellows |
| 2021 | NewSchools Venture Fund | $2,500,000 | Special Projects |
| 2021 | Trellis Education | $400,000 | Special Projects |
| 2021 | Catholic Legal Immigration Network, Inc. | $400,000 | Democracy |
| 2021 | International Rescue Committee, Inc. | $300,000 | Special Projects |
| 2021 | Center for Strategic and International Studies, Inc. | $250,000 | International Peace and Security |
| 2021 | National Science Teaching Association | $100,000 | Education |
| 2021 | Education Sub Saharan Africa | $390,000 | Higher Education and Research in Africa |
| 2021 | Institute for Security and Technology, Inc | $200,000 | International Peace and Security |
