| 2021 | James B. Hunt, Jr. Institute for Educational Leadership and Policy Foundation, Inc. | $500,000 | Special Projects |
| 2021 | OneGoal | $200,000 | Education |
| 2021 | MDRC | $500,000 | Education |
| 2021 | Nuclear Threat Initiative Inc. | $1,800,000 | International Peace and Security |
| 2021 | Windward Fund | $200,000 | Democracy |
| 2021 | EdReports.org | $400,000 | Education |
| 2021 | Columbia University | $600,000 | International Peace and Security |
| 2021 | Braven | $300,000 | Education |
| 2021 | United States Military Academy | $280,000 | International Peace and Security |
| 2021 | University of Maryland | $335,000 | International Peace and Security |
| 2021 | 2Revolutions | $200,000 | Education |
| 2021 | Open Earth Foundation | $500,000 | International Peace and Security |
| 2021 | University Of South Carolina | $200,000 | Education |
| 2021 | Shana Kushner Gadarian | $200,000 | Andrew Carnegie Fellows |
| 2021 | Sonali McDermid | $200,000 | Andrew Carnegie Fellows |
| 2021 | Elizabeth Ananat | $200,000 | Andrew Carnegie Fellows |
| 2021 | Richard Bell | $200,000 | Andrew Carnegie Fellows |
| 2021 | Jessica Shoemaker | $200,000 | Andrew Carnegie Fellows |
| 2021 | Christine Folch | $200,000 | Andrew Carnegie Fellows |
| 2021 | Deborah Boehm | $200,000 | Andrew Carnegie Fellows |
| 2021 | Leonce Ndikumana | $200,000 | Andrew Carnegie Fellows |
| 2021 | CAB International | $125,000 | Higher Education and Research in Africa |
| 2021 | Caroline Tolbert | $200,000 | Andrew Carnegie Fellows |
| 2021 | Global Platform for Higher Education in Emergencies | $200,000 | International Peace and Security |
| 2021 | Americans for Oxford | $200,000 | Special Projects |
